These new medications have given rise to a number of different opioid detox treatment approaches. Whether heroin or prescription painkillers are the opioid of choice, inpatient care or medication is often recommended for optimum comfort and safety. In instances where money is an issue or the patient must stay engaged at work or home, coming into an outpatient detox program regularly could provide adequate treatment. The desire to use the drug of choice in order to stop the withdrawal symptoms is strong. The existence of co-occurring physical or mental disorders.